Principal Research Scientist I, Automation Strategy Lead for Biologics CMC Development

Company: AbbVie
Location: San Francisco
Posted on: February 12, 2026

Job Description:

Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on X , Facebook , Instagram , YouTube , LinkedIn and Tik Tok . Job Description Overview: The Biologics CMC Development team at AbbVie in the Bay Area has a long and rich history of biologics development. Located in a state-of-the-art facility in South San Francisco, the team leverages its comprehensive end-to-end CMC capabilities to work collaboratively through all phases of CMC development with a primary focus on advancing complex biologic therapies, such as bi-specifics and novel modalities, to human clinical studies and eventual licensure. This role is within a team of highly experienced scientists and managers who have directly enabled the development/IND submissions of 20 novel oncology drugs and successfully filed two BLAs. The Principal Automation Technology Strategy Lead will serve as the cross-functional architect and owner of the holistic laboratory equipment automation roadmap for Biologics CMC Development at AbbVies South San Francisco site. This pivotal role integrates technical vision, hands-on system expertise, leadership, and change management across all CMC functions to accelerate productivity, drive high system uptime, improve data quality, and foster an innovative, future-ready automation culture. The Strategy Lead will act as an influential individual contributor with potential for future team leadership, and as AbbVies connector to the broader automation community internally and externally. Key Responsibilities: Architect, lead, and implement the equipment automation roadmap at the Biologics CMC Development at AbbVies South San Francisco site, with influence extending across Cell Line, Cell Culture, Purification, Formulation, and Analytical Development. Lead cross-functional automation assessments and strategic prioritization exercises to identify workflow automation opportunities including but not limited to liquid handling, integrated data management, compound management, robotics, and equipment connectivity. Collaborate with equipment vendors, IT/digital teams, and data transformation initiatives to roadmap and orchestrate solutions maximizing interoperability, scalability, and future-readiness of the technology ecosystem. Oversee system uptime and performance, developing robust monitoring and continuous improvement processes; establish, track, and deliver on process improvement milestones. Identify, pilot, and scale automation technology solutionsincluding hardware, software, and integration strategies (Tecan, Hamilton, Lynx, Agilent, Opentron, etc.)tailored to a rapidly evolving scientific environment. Collaborate closely with scientific leaders, technical experts, and bench scientists to map workflows, capture requirements, and deliver integrated automation solutions, balancing short- and long-term site objectives. Serve as the primary interface with compound management to streamline sample and data management systems, maximizing traceability, efficiency, and reliability. Understands the business implications of assigned projects and processes and identifies automation solutions compatible with business needs. Lead troubleshooting and problem-solving efforts for challenging or novel automation system failures, working closely with technology partners and vendors as needed Act as a mentor and key resource for technical staff, supporting training, user acceptance testing, and the adoption of best practices across user groups. Connect AbbVies site teams with the global automation communityimporting, adapting, and sharing innovations, standards, and lessons learned. Build relationships with vendors and technology partners; maintain awareness of industry trends and proactively evaluate new solutions for strategic fit. Ensure thorough documentation, compliance, and knowledge management consistent with AbbVie policies. Qualifications Degree in Engineering, Computer Science, Chemistry, Biochemistry, Biological Sciences, or related technical field with 14(BS), 10(MS), or 6(PhD) years of experience. Minimum 6 years progressive experience in laboratory automation strategy/implementation in a pharmaceutical, biotechnology or closely related environment Proven record of delivering and maintaining integrated lab automation solutions including both hardware and software across platforms (liquid handlers, robotics, readers, etc.). Demonstrated success leading cross-functional automation initiatives, from design and pilot phases through scaling and full integration into routine laboratory operations, with measurable impacts in system uptime, data quality, and process improvement. Hands-on experience with one or more liquid handling systems (Hamilton, Agilent, Tecan, Lynx, and/or Opentron) and managing high-volume data/sample workflows. Strong technical skills in system integration, scripting/coding, and mechanical troubleshooting Record of measurable impact in performance improvements: system uptime, data quality, process metrics, and end-user satisfaction. Excellent critical thinking, problem-solving, and influencing abilities; demonstrated capacity to drive consensus and change in a matrixed, cross-functional environment. Excellent written, verbal, and presentation skills, able to communicate across organizational levels History of productive collaboration in a dynamic, fast-paced, cross-functional environment Proactive participant/connector in automation professional networks within the broader automation community Knowledge of compliance standards and documentation in regulated laboratory settings Active participant in professional automation networks or external communities. Preferred Qualifications: Experience delivering automated lab solutions specifically for one or more CMC development functions (Cell Line, Cell Culture, Purification, Formulation, and Analytical Development) Demonstrated experience mentoring technical staff and/or prior management or team leadership experience Leveling will be commensurate to experience . Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible to participate in our short-term incentiveprograms. Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html

Keywords: AbbVie, Modesto , Principal Research Scientist I, Automation Strategy Lead for Biologics CMC Development, Engineering , San Francisco, California